Abstract Approved antibody-drug conjugates (ADCs) for HER2-positive breast cancer include trastuzumab emtansine and trastuzumab deruxtecan.To develop a differentiated HER2 ADC, we chose an antibody that does not compete with trastuzumab or pertuzumab for binding, conjugated to a reduced potency PBD (pyrrolobenzodiazepine) dimer payload.PBDs are pot
Bone mineral density scans in veterans
Elizabeth Bass1,2, Etienne Pracht1,3, Philip Foulis4,51VISN 8 Patient billy-royal-double-diamond-two-ear-headstall/ Safety Center of Inquiry, Tampa, FL; 2School of Aging Studies, University of South Florida, Tampa, FL, USA; 3College of Public Health, University of South Florida, Tampa, FL, USA; 4James A Haley VA Hospital, Tampa, FL, USA; 5Pathology
MODELS OF GENERATION OF INPUT DATA OF TRAINING OF NEURAL NETWORK MODULES FOR DIAGNOSTIC OF DISEASES IN UROLOGY
The subject of the research presented in the article is neural network modules (NNMs), which are used to solve problems in the practice of diagnosing diseases in urology.This work aims to develop a mathematical model for generating a multitude of uroflowmetric parameters, in particular, graphs of uroflowrograms of Boyfriend Jean the required volume
P2X7 receptor is essential for cross-dressing of bone marrow-derived dendritic cells
Summary: T cell activation requires the processing and presentation of antigenic peptides in Dish cloth the context of a major histocompatibility complex (MHC complex).Cross-dressing is a non-conventional antigen presentation mechanism, involving the transfer of preformed peptide/MHC complexes from whole cells, such as apoptotic cells (ACs) to the